Minoru Suzuki Selected Research

Cytochalasin B

3/2006	Evaluation of hypoxic cell radio-sensitizers in terms of radio-sensitizing and repair-inhibiting potential. Dependency on p53 status of tumor cells and the effects on intratumor quiescent cells.
2/2006	Evaluation of hypoxia-specific cytotoxic bioreductive agent-sodium borocaptate-10B conjugates as 10B-carriers in boron neutron capture therapy.
8/2005	Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of tumor cells.
11/2004	Combination of the vascular targeting agent ZD6126 with boron neutron capture therapy.
10/2004	Effects of mild temperature hyperthermia and p53 status on the size of hypoxic fractions in solid tumors, with reference to the effect in intratumor quiescent cell populations.
9/2004	Applicability of the 2-nitroimidazole-sodium borocaptate-10B conjugate, TX-2060, as a 10B-carrier in boron neutron capture therapy.
5/2003	Effects of p53 status and wortmannin treatment on potentially lethal damage repair, with emphasis on the response of intratumor quiescent cells.
1/2003	Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors: its independence of p53 status.
1/2003	Potential of alpha-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers.

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Minoru Suzuki Research Topics

Disease

148	Neoplasms (Cancer) 05/2024 - 01/2003
28	Glioma (Gliomas) 04/2024 - 06/2003
16	Brain Neoplasms (Brain Tumor) 09/2023 - 05/2007
13	Melanoma (Melanoma, Malignant) 03/2022 - 04/2006
12	Glioblastoma (Glioblastoma Multiforme) 04/2024 - 06/2003
12	Hyperthermia 12/2019 - 01/2003
11	Hypoxia (Hypoxemia) 01/2021 - 10/2004
9	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2023 - 11/2004
9	Neoplasm Metastasis (Metastasis) 11/2020 - 10/2007
8	Head and Neck Neoplasms (Head and Neck Cancer) 11/2023 - 06/2003
6	Malignant Mesothelioma 08/2023 - 12/2006
6	Squamous Cell Carcinoma of Head and Neck 01/2016 - 05/2004
5	Necrosis 05/2022 - 01/2010
4	Body Weight (Weight, Body) 01/2023 - 05/2004
4	Clear Cell Sarcoma 12/2020 - 03/2013
4	Hepatocellular Carcinoma (Hepatoma) 09/2020 - 05/2007
3	Carcinoma (Carcinomatosis) 01/2024 - 11/2004
3	Fibrosis (Cirrhosis) 10/2022 - 07/2020
3	Meningioma (Meningiomas) 01/2022 - 07/2016
3	Liver Neoplasms (Liver Cancer) 11/2021 - 06/2014
3	Lymphatic Metastasis 04/2018 - 10/2007
3	Alzheimer Disease (Alzheimer's Disease) 01/2017 - 04/2003
2	Liver Cirrhosis (Hepatic Cirrhosis) 10/2022 - 12/2020
2	Radiation Injuries (Radiation Sickness) 10/2022 - 05/2022
2	Disease Progression 05/2022 - 07/2020
2	Lymphedema (Milroy Disease) 07/2020 - 05/2007
2	Varicose Veins (Varicose Vein) 01/2016 - 11/2009
2	Neurofibrosarcoma (MPNST) 12/2015 - 12/2010
2	Prostatic Neoplasms (Prostate Cancer) 01/2015 - 05/2006
2	Aneurysm (Aneurysms) 01/2013 - 01/2007

Drug/Important Bio-Agent (IBA)

52	BoronIBA 05/2024 - 05/2004
37	Bromodeoxyuridine (BrdU)IBA 03/2023 - 01/2003
17	SodiumIBA 03/2023 - 05/2004
9	SuspensionsIBA 01/2021 - 01/2003
9	Cytochalasin BIBA 03/2006 - 01/2003
8	Amino Acid Transport Systems (Amino Acid Transporter)IBA 05/2024 - 01/2020
8	4-boronophenylalanineIBA 04/2024 - 03/2013
8	Therapeutic UsesIBA 12/2023 - 01/2011
8	Niacinamide (Nicotinamide)FDA LinkGeneric 12/2019 - 10/2004
8	Tirapazamine (SR 4233)IBA 12/2019 - 01/2003
7	Liposomes (Liposome)IBA 10/2023 - 12/2006
7	mercaptoundecahydrododecaborate (borocaptate sodium)IBA 01/2021 - 03/2004
7	EmulsionsIBA 09/2020 - 03/2004
6	GadoliniumIBA 12/2023 - 06/2014
6	LipidsIBA 11/2023 - 01/2016
6	Proteins (Proteins, Gene)FDA Link 02/2023 - 04/2003
6	Boron-10IBA 02/2023 - 11/2009
6	Phenylalanine (L-Phenylalanine)FDA Link 01/2023 - 07/2009
6	Bevacizumab (Avastin)FDA Link 05/2022 - 03/2013
5	Amino Acids FDA Link 05/2024 - 08/2012
5	AlbuminsIBA 12/2023 - 10/2016
5	FructoseIBA 10/2023 - 01/2020
5	Cytotoxins (Cytolysins)IBA 12/2019 - 08/2005
5	WortmanninIBA 06/2019 - 05/2003
5	Cisplatin (Platino)FDA LinkGeneric 01/2010 - 05/2002
4	dodecaborateIBA 09/2023 - 10/2016
4	Peptides (Polypeptides)IBA 01/2021 - 06/2006
4	pimonidazoleIBA 10/2017 - 10/2010
4	Oxygen (Dioxygen)IBA 01/2016 - 10/2004
4	CarbonIBA 08/2015 - 01/2008
3	Biomarkers (Surrogate Marker)IBA 05/2024 - 01/2011
3	SolutionsIBA 07/2023 - 12/2006
3	LigandsIBA 04/2023 - 10/2020
3	IntegrinsIBA 02/2023 - 06/2012
3	AcidsIBA 01/2023 - 12/2014
3	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 05/2011
3	Boron CompoundsIBA 03/2014 - 05/2004
3	N-acetylcochinol-O-phosphateIBA 01/2007 - 11/2004
3	Ethiodized Oil (Ethiodol)FDA Link 11/2004 - 03/2004
2	Sorbitol (Yal)FDA Link 11/2023 - 07/2023
2	PolymersIBA 11/2023 - 10/2021
2	Phospholipases A2 (Phospholipase A2)IBA 01/2022 - 01/2010
2	maleimideIBA 01/2022 - 10/2016
2	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 12/2021 - 11/2021
2	Transferrin (beta 2 Transferrin)IBA 11/2021 - 12/2006
2	Lysine (L-Lysine)FDA Link 10/2021 - 10/2016
2	Ethylene Glycol (Monoethylene Glycol)IBA 10/2021 - 01/2017
2	AnnexinsIBA 01/2021 - 01/2021
2	Hyaluronic Acid (Hyaluronan)IBA 01/2021 - 03/2016
2	ChitosanIBA 10/2020 - 06/2014
2	Caffeine (No Doz)FDA LinkGeneric 06/2019 - 03/2013
2	Gadolinium DTPA (Magnevist)FDA Link 04/2016 - 06/2015
2	calcium phosphateIBA 04/2016 - 06/2015
2	MicellesIBA 06/2015 - 05/2012
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 03/2015 - 03/2015
2	Angiogenesis InhibitorsIBA 03/2013 - 02/2007

Therapy/Procedure

113	Boron Neutron Capture Therapy 05/2024 - 03/2004
29	Radiotherapy 04/2024 - 06/2003
27	Therapeutics 05/2024 - 01/2003
15	Neutron Capture Therapy 12/2023 - 03/2008
5	Intra-Arterial Injections 11/2021 - 12/2011
5	Drug Therapy (Chemotherapy) 01/2014 - 10/2007
4	Chemoradiotherapy 05/2024 - 05/2002
4	Nuclear Reactors 03/2022 - 04/2016
3	Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated) 02/2008 - 06/2003
2	Intravenous Administration 02/2023 - 01/2022
2	Intravenous Injections 01/2023 - 01/2021
2	Re-Irradiation 05/2022 - 01/2021
2	Intraperitoneal Injections 12/2019 - 01/2003
2	Photochemotherapy (Photodynamic Therapy) 03/2015 - 03/2015